With so much attention focused on the dangers of opioid painkillers, it's easy to forget that even "safe" over-the-counter products carry some dangers.
If you don't think twice about reaching for a pill to relieve aches and pains, especially medicines called nonsteroidal anti-inflammatory drugs, or NSAIDs, you need to know about the wide-ranging cautions surrounding their use, especially if you take them on a regular basis and over a long period of time.
NSAIDs can cause:
NSAIDs can also increase the chance of a heart attack or stroke, even within just the first few weeks of using one, and the risk can rise over time. Your risk for heart issues is greater if you have high blood pressure or heart disease or recently had a heart attack or bypass surgery. Aspirin is the one NSAID this warning doesn't apply to. However, NSAIDs, including aspirin, can damage the stomach lining and cause gastrointestinal (GI) tract bleeding and ulcers.
Your risk for GI issues is higher if you:
If you're considering acetaminophen, commonly known by the brand name Tylenol, as an alternative to NSAIDs, know that acetaminophen can also cause severe liver damage, according to the U.S. Food and Drug Administration. Like NSAIDs, it's also in hundreds of other products, so as with all drugs, read medication ingredient labels to avoid taking too much of the same active ingredient and potentially overdosing.
In general, always take the lowest effective dose for the shortest amount of time possible, and only after talking to your doctor if you already have high blood pressure or any other chronic condition.
The FDA has more on NSAIDs and new cautions.